Mandlekar, Sandhya: search on Z-Library

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1

Signal transduction events elicited by natural products: Role of MAPK and caspase pathways in homeostatic response and induction of apoptosis

Ah-Ng Tony Kong, Rong Yu, Chi Chen, Sandhya Mandlekar, Thomas Primiano

Journal:

Archives of Pharmacal Research

Year:

2000

Language:

english

File:

PDF, 1.66 MB

english, 2000

2

Signal transduction events elicited by cancer prevention compounds

Ah-Ng Tony Kong, Rong Yu, Vidya Hebbar, Chi Chen, Edward Owuor, Rong Hu, Rachel Ee, Sandhya Mandlekar

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2001

Language:

english

File:

PDF, 161 KB

english, 2001

3

Modulation of Metabolic Enzymes by Dietary Phytochemicals: A Review of Mechanisms Underlying Beneficial Versus Unfavorable Effects

Mandlekar, Sandhya, Hong, Jin-Liern, Tony Kong, Ah-Ng

Journal:

Current Drug Metabolism

Year:

2006

Language:

english

File:

PDF, 95 KB

english, 2006

4

(Carbonyl)oxyalkyl linker-based amino acid prodrugs of the HIV-1 protease inhibitor atazanavir that enhance oral bioavailability and plasma trough concentration

Subbaiah, Murugaiah A.M., Ramar, Thangeswaran, Subramani, Lakshumanan, Desai, Salil D., Sinha, Sarmistha, Mandlekar, Sandhya, Jenkins, Susan M., Krystal, Mark R., Subramanian, Murali, Sridhar, Srikant

Journal:

European Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 2.48 MB

2020

5

LC–MS determination of triazolam and its hydroxy metabolites in mouse dried blood spots: application to transgenic mouse pharmacokinetic studies

Kole, Prashant, Rao, Abhijith, Kurawattimath, Vishwanath, Mandlekar, Sandhya

Journal:

Year:

2017

Language:

english

File:

PDF, 1.20 MB

english, 2017

6

Erratum to: A modified serial blood sampling technique and utility of dried-blood spot technique in estimation of blood concentration: application in mouse pharmacokinetics

Vishwanath Kurawattimath, Krishna Pocha, T. Thanga Mariappan, Ravi Kumar Trivedi, Sandhya Mandlekar

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2011

Language:

english

File:

PDF, 95 KB

english, 2011

7

Induction of xenobiotic enzymes by the map kinase pathway and the antioxidant or electrophile response element (ARE/EpRE)1*2 ,†, 3 ‡

Kong, A.-N. Tony, Owuor, Edward, Yu, Rong, Hebbar, Vidya, Chen, Chi, Hu, Rong, Mandlekar, Sandhya

Journal:

Drug Metabolism Reviews

Year:

2001

Language:

english

File:

PDF, 205 KB

english, 2001

8

Electrophilicity of Pyridazine-3-carbonitrile, Pyrimidine-2-carbonitrile, and Pyridine-carbonitrile Derivatives: A Chemical Model To Describe the Formation of Thiazoline Derivatives in Human Liver Microsomes

Sinha, Sarmistha, Ahire, Deepak, Wagh, Santosh, Mullick, Dibakar, Sistla, Ramesh, Selvakumar, Kumaravel, Cortes, Janet Caceres, Putlur, Siva Prasad, Mandlekar, Sandhya, Johnson, Benjamin M.

Journal:

Chemical Research in Toxicology

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

9

A Simplified Protocol Employing Elacridar in Rodents: A Screening Model in Drug Discovery to Assess P-gp Mediated Efflux at the Blood Brain Barrier

Kallem, Rajareddy, P. Kulkarni, Chetan, Patel, Dakshay, Thakur, Megha, Sinz, Michael, P. Singh, Sheelendra, Shahe Mahammad, S., Mandlekar, Sandhya

Journal:

Drug Metabolism Letters

Year:

2012

Language:

english

File:

PDF, 683 KB

english, 2012

10

Discovery of Disubstituted Cyclohexanes as a New Class of CC Chemokine Receptor 2 Antagonists

Cherney, Robert J., Mo, Ruowei, Meyer, Dayton T., Nelson, David J., Lo, Yvonne C., Yang, Gengjie, Scherle, Peggy A., Mandlekar, Sandhya, Wasserman, Zelda R., Jezak, Heather, Solomon, Kimberly A., Tebb

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 110 KB

english, 2008

11

Metabolite Identification, Reaction Phenotyping and Retrospective Drug-Drug Interaction Predictions of 17-deacetylnorgestimate, the Active Component of the Oral Contraceptive Norgestimate

Ahire, Deepak, Sinha, Sarmistha, Brock, Barry, Iyer, Ramaswamy, Mandlekar, Sandhya, Subramanian, Murali

Journal:

Drug Metabolism and Disposition

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

12

Discovery and Lead Optimization of a Novel Series of CC Chemokine Receptor 1 (CCR1)-Selective Piperidine Antagonists via Parallel Synthesis

Cavallaro, Cullen L., Briceno, Stephanie, Chen, Jing, Cvijic, Mary Ellen, Davies, Paul, Hynes, John, Liu, Rui-Qin, Mandlekar, Sandhya, Rose, Anne V., Tebben, Andrew J., Van Kirk, Katy, Watson, Andrew,

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.71 MB

english, 2012

13

Signalling in cell survival and cell death

A.-N.Tony Kong, RongYu, Sandhya Mandlekar

Journal:

Year:

2000

Language:

english

File:

PDF, 200 KB

english, 2000

14

Pharmacodynamics and Toxicodynamics of Drug Action: Signaling in Cell Survival and Cell Death

Ah-Ng Tony Kong, Sandhya Mandlekar, Rong Yu, Wei Lei, Adedigbo Fasanmande

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.96 MB

1999

15

A novel raft-forming antacid suspension using a natural dietary fibre

Sandhya V. Mandlekar, Suneeta S. Marathe, Padma V. Devarajan

Journal:

International Journal of Pharmaceutics

Year:

1997

Language:

english

File:

PDF, 270 KB

english, 1997

16

Estimation of the Unbound Brain Concentration of P-Glycoprotein Substrates or Nonsubstrates by a Serial Cerebrospinal Fluid Sampling Technique in Rats

Mariappan, T. Thanga, Kurawattimath, Vishwanath, Gautam, Shashyendra Singh, Kulkarni, Chetan P., Kallem, Rajareddy, Taskar, Kunal S., Marathe, Punit H., Mandlekar, Sandhya

Journal:

Molecular Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 306 KB

english, 2014

17

Practical and Economical Implementation of Online H/D Exchange in LC-MS

Shah, Ravi P., Garg, Amit, Putlur, Siva Prasad, Wagh, Santosh, Kumar, Vineet, Rao, Venugopala, Singh, Saranjit, Mandlekar, Sandhya, Desikan, Sridhar

Journal:

Analytical Chemistry

Year:

2013

Language:

english

File:

PDF, 3.18 MB

english, 2013

18

Alkylsulfone-containing trisubstituted cyclohexanes as potent and bioavailable chemokine receptor 2 (CCR2) antagonists

Cherney, Robert J., Mo, Ruowei, Yang, Michael G., Xiao, Zili, Zhao, Qihong, Mandlekar, Sandhya, Cvijic, Mary Ellen, Charo, Israel F., Barrish, Joel C., Decicco, Carl P., Carter, Percy H.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 482 KB

english, 2014

19

Design, Synthesis, and Pharmacokinetic Evaluation of Phosphate and Amino Acid Ester Prodrugs for Improving the Oral Bioavailability of the HIV-1 Protease Inhibitor Atazanavir

A. M. Subbaiah, Murugaiah, Mandlekar, Sandhya, Desikan, Sridhar, Ramar, Thangeswaran, Subramani, Lakshumanan, Annadurai, Mathiazhagan, Desai, Salil D., Sinha, Sarmistha, Jenkins, Susan M., Krystal, Ma

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 1.04 MB

english, 2019

20

Discovery of an orally-bioavailable CC Chemokine Receptor 2 antagonist derived from an acyclic diaminoalcohol backbone

Percy H. Carter, Gregory D. Brown, Sarah R. King, Matthew E. Voss, Andrew J. Tebben, Robert J. Cherney, Sandhya Mandlekar, Yvonne C. Lo, Gengjie Yang, Persymphonie B. Miller, Peggy A. Scherle, Qihong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 469 KB

english, 2012

21

Discovery of a Potent and Orally Bioavailable Dual Antagonist of CC Chemokine Receptors 2 and 5

Carter, Percy H., Brown, Gregory D., Cherney, Robert J., Batt, Douglas G., Chen, Jing, Clark, Cheryl M., Cvijic, Mary Ellen, Duncia, John V., Ko, Soo S., Mandlekar, Sandhya, Mo, Ruowei, Nelson, David

Journal:

ACS Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 429 KB

english, 2015

22

Coproporphyrin-I: A Fluorescent, Endogenous Optimal Probe Substrate for ABCC2 (MRP2) Suitable for Vesicle-Based MRP2 Inhibition Assay

Gilibili, Ravindranath Reddy, Chatterjee, Sagnik, Bagul, Pravin, Mosure, Kathleen W., Murali, Bokka Venkata, Mariappan, T. Thanga, Mandlekar, Sandhya, Lai, Yurong

Journal:

Drug Metabolism and Disposition

Year:

2017

Language:

english

File:

PDF, 5.36 MB

english, 2017

23

Absolute quantification of imipramine and its metabolites in vivo utilizing calibrators from radiolabeled in vitro incubations

Bhutani, Priyadeep, Shah, Devang, Varkhede, Ninad, Mandlekar, Sandhya, Chacko, Silvi, Subramanian, Murali

Journal:

Year:

2016

Language:

english

File:

PDF, 1.21 MB

english, 2016

24

Spotting of external calibration standards on blank dried blood spots as a resource sparing protocol

Nigam, Anuja, Kole, Prashant, Kurawattimath, Vishwanath, Mandlekar, Sandhya, Subramanian, Murali

Journal:

Year:

2017

Language:

english

File:

PDF, 980 KB

english, 2017

25

Unmasking the Role of Uptake Transporters for Digoxin Uptake Across the Barriers of the Central Nervous System in Rat

Taskar, Kunal S, Mariappan, T Thanga, Kurawattimath, Vishwanath, Singh Gautam, Shashyendra, Radhakrishna Mullapudi, TV, Sridhar, Srikanth K, Kallem, Raja Reddy, Marathe, Punit, Mandlekar, Sandhya

Journal:

Journal of Central Nervous System Disease

Year:

2017

Language:

english

File:

PDF, 823 KB

english, 2017

26

Insight into Tissue Unbound Concentration: Utility in Drug Discovery and Development

Thanga Mariappan, T., Mandlekar, Sandhya, Marathe, Punit

Journal:

Current Drug Metabolism

Year:

2013

Language:

english

File:

PDF, 639 KB

english, 2013

27

Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells

Shtil, Alexander A, Mandlekar, Sandhya, Yu, Rong, Walter, Robert J, Hagen, Karen, Tan, Tse-Hua, Roninson, Igor B, Kong, Ah-Ng Tony

Journal:

Year:

1999

Language:

english

File:

PDF, 482 KB

english, 1999

28

Prediction of pH dependent absorption using in vitro, in silico, and in vivo rat models: Early liability assessment during lead optimization

Saxena, Ajay, Shah, Devang, Padmanabhan, Shweta, Gautam, Shashyendra Singh, Chowan, Gajendra Singh, Mandlekar, Sandhya, Desikan, Sridhar

Journal:

European Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 1.33 MB

english, 2015

29

Discovery of 5-phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)quinazolin-4-amine as a potent I Kur inhibitor

Finlay, Heather J., Johnson, James A., Lloyd, John L., Jiang, Ji, Neels, James, Gunaga, Prashantha, Banerjee, Abhisek, Dhondi, Naveen, Chimalakonda, Anjaneya, Mandlekar, Sandhya, Conder, MaryLee, Sale

Journal:

ACS Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 201 KB

english, 2016

30

Relative quantitation of endogenous proteins by quadrupole-time of flight and tandem mass spectrometry

Gautam, Shashyendra Singh, Wagh, Santosh, Babu, Suresh, Gudihal, Ravindra, Rajagopalan, Sudha, Kole, Prashant, Mandlekar, Sandhya, Subramanian, Murali

Journal:

Journal of Chromatography B

Year:

2019

Language:

english

File:

PDF, 1.69 MB

english, 2019

31

A modified serial blood sampling technique and utility of dried-blood spot technique in estimation of blood concentration: application in mouse pharmacokinetics

Vishwanath Kurawattimath, Krishna Pocha, T. Thanga Mariappan, Ravi Kumar Trivedi, Sandhya Mandlekar

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2012

Language:

english

File:

PDF, 333 KB

english, 2012

32

Conference Report: Applied Pharmaceutical Analysis India 2013 Conference Report

Kole, Prashant, Shedbalkar, Vinay, Raina, Vijay, Subramanian, Murali, Barot, Deepak, Mandlekar, Sandhya

Journal:

Year:

2013

Language:

english

File:

PDF, 323 KB

english, 2013

33

Single jugular vein cannulated rats may not be suitable for intravenous pharmacokinetic screening of high logP compounds

Gaud, Nilesh, Kumar, Anoop, Matta, Muralikrishna, Kole, Prashant, Sridhar, Srikanth, Mandlekar, Sandhya, Holenarsipur, Vinay K.

Journal:

European Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 805 KB

english, 2017

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